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What are the uses of 1,2-bis (bromoacetoxy) ethane

Sources:www.worldbrom.com | PublishDate:2026.02.06

      1,2-Bis (bromoacetoxy) ethane is an important organic synthesis intermediate, which contains two highly active bromoacetoxy functional groups in its molecular structure. Its main applications are concentrated in the fields of polymer materials, biomedicine, and chemical engineering, as follows:
1、 Polymer materials field (core applications)
1. Crosslinking agent and curing agent
      As a bifunctional crosslinking agent, it is used for curing reactions of resins such as epoxy resin, polyurethane, and acrylic ester. Its two bromoacetoxy groups can undergo nucleophilic substitution reactions with active groups such as hydroxyl and amino groups in the resin, forming a three-dimensional network structure that significantly improves the hardness, heat resistance, chemical corrosion resistance, and mechanical strength of the material. It is suitable for the preparation of high-performance coatings, adhesives, and composite materials.
2. Polymer modifier
      Used for graft modification of polymers such as polyolefins and polyesters, introducing bromoacetoxy functional groups to improve the hydrophilicity, adhesion, and compatibility with other materials of polymers, expanding their applications in printing, packaging, biomedical materials, and other fields.
2、 Biomedical field
1. Intermediate for drug synthesis
      Used for synthesizing anti-tumor, antibacterial, antiviral and other drug molecules. Its dual functional group structure can serve as a connecting arm, linking different pharmacophores through ether bonds, ester bonds, etc., to construct drug precursors with targeting or synergistic effects; It can also be used as a modifier for synthesizing peptides and nucleic acid drugs, regulating the stability and bioavailability of drugs.
2. Biological probes and crosslinking agents
      As a crosslinking agent for biomolecules such as proteins, enzymes, and antibodies, it achieves the fixation, labeling, or coupling of biomolecules through the reaction of bromoacetoxy with thiol and amino groups in biomolecules, and is used for biological detection, immunoassay, and drug carrier construction.
3、 Chemical Engineering and Organic Synthesis
1. Organic synthetic blocks
      As an important C4 synthesizer, it is used to construct complex organic molecules. Its two active bromine atoms can undergo substitution, elimination, addition and other reactions, introducing functional groups such as hydroxyl, amino, carboxyl, etc. It is a key intermediate for the synthesis of fragrances, dyes, pesticides and other chemicals.
2. Synthesis of Ionic Liquids and Surfactants
      Used for synthesizing functional ionic liquids or cationic surfactants, introducing bromoacetoxy groups through quaternization reactions, endowing the products with good solubility, antibacterial properties, and surface activity, and applied in fields such as electrochemistry, catalysis, and daily chemical products.
4、 Other applications
1. Rubber additives
      As a rubber vulcanization accelerator or crosslinking agent, it enhances the vulcanization efficiency and crosslinking density of rubber, improves the wear resistance and aging resistance of rubber, and is suitable for special rubber products.
2. Electronic chemicals
      Used for the synthesis of photoresist and electronic packaging materials, its high reactivity and structural stability can meet the requirements of high-precision and high reliability in the electronic field.